Neal Page, a frazzled and time-sensitive marketing executive, finds himself unexpectedly thrown together with Del Griffith, an amiable yet persistent shower curtain ring salesman, on a seemingly endless journey to their shared destination of Chicago during the Thanksgiving holiday. Despite their contrasting personalities and careers - one a harried city worker and the other a cheerful road-warrior - the two men embark on a series of hilarious misadventures and impromptu detours due to various transportation mishaps. As they navigate this unpredictable odyssey, Neal and Del's initial frustration slowly gives way to a surprising camaraderie that showcases the power of human connection amidst life's inevitable twists and turns.
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